Farming and Ranching

A guide for farmers and ranchers with alpha-gal syndrome

Farmers and Ranchers: an At-Risk Population

Ten percent of Americans are bitten by a tick each year. But farmers and ranchers have much more exposure to ticks. Almost three-quarters of all farmers receive tick bites each year.

In addition, many of the top cattle-producing areas fall within states and counties with the highest densities of lone star ticks.

For these reasons, farmers and ranchers are at disproportionate risk of developing alpha-gal syndrome.

Alpha-gal syndrome and caring for livestock

We report the cases of 3 known α-gal–allergic patients who experienced allergic reactions on exposure to amniotic fluid when assisting during calving. Patients 1 and 2 experienced contact urticaria limited to exposed areas, while patient 3 also experienced dyspnea, probably due to inhalation of amniotic fluid proteins. The severity of the symptoms prevented the patients from continuing to assist the veterinarian during calf delivery. The laboratory results enabled us to identify several proteins in the amniotic fluid that were recognized by the IgE of the patients’ serum, pointing to α-gal as the etiologic agent.

Nuñez-Orjales R, Martin-Lazaro J, Lopez-Freire S, Galan-Nieto A, Lombardero-Vega M, Carballada-Gonzalez F. Bovine Amniotic Fluid: A New and Occupational Source of Galactose-α-1,3-Galactose. J Investig Allergol Clin Immunol. 2017;27(5):313-314.

Livestock like cows, pigs, sheep, and goats are mammals and make alpha-gal. For this reason, for farmers and ranchers, alpha-gal syndrome (AGS) is not just a food and drug allergy; it’s also an occupational allergy.

Just as people allergic to pets, like cats and dogs, react when exposed to them, people with AGS can react from livestock exposures. Although it is not an issue for all farmers and ranchers with AGS, some have severe, life-threatening reactions to some livestock exposures.

Livestock fluids

Livestock fluids are particularly problematic for people with AGS.

Amniotic fluid and blood

Exposure to both amniotic fluid and blood can cause life-threatening reactions in people with AGS. Care needs to be taken during calving, care of newly born animals, processing of carcasses, and other activities they may result in exposure to these fluids.

Saliva

Farmers with AGS report reactions to livestock saliva as well. Typical reactions include hives and swelling.

Waste

Farmers and ranchers report reactions to both direct contact with waste and to fumes from waste.

Direct contact

Direct contact with livestock can lead to reactions for some farmers. For example:

  • During milking
  • Contact with hair–especially sheep’s wool (due to lanolin)

Airborne exposures

Many farmers report reactions to airborne exposures, including from amniotic fluid and waste. 

Reactions to products used in livestock care

Some farmers report reactions to products used in the care of livestock, especially lanolin-based products applied to the udders of milking cows.

Coping strategies

Some measures you can take:

  • Wear protective gear to protect your skin.
  • Respirators may help protect against airborne exposures–if they fit well.
  • Make sure you have your rescue medications, and use them if you need to.
  • Don’t work alone, when possible.
  • Shower as soon as possible after an exposure.
  • Wash chore clothing contaminated with amniotic fluid, blood, or manure separately.

Media

Webinars

Webinar: Tick Bites, Meat Allergy, and Caring for Livestock: What Farmers and Ranchers Need to Know

April 24 @ 12:00 pm  1:00 pm CDT

Summary: Alpha-gal syndrome (AGS)  is an emerging tick-borne allergy to alpha-gal, a sugar found in mammals and products derived from them. These products include food, drugs, personal care and other products. Up to half a million Americans are estimated to be affected by AGS; most live in high-prevalence states in the South, Midwest, and East Coast.

Farmers are at higher risk of tick bites and developing AGS. For farmers, AGS is not just a food allergy, it’s an occupational allergy. Reactions fluids, waste, and dander from livestock can make caring for them difficult. In this seminar, we will provide an introduction to AGS, share tips on avoiding it, and hear from farmers and ranchers about the challenges of farming with AGS and how to manage them.

Objectives: At the end of this webinar, participants will understand…

  1. The basics of alpha-gal syndrome
  2. When and how to seek a diagnosis
  3. How farmers cope with AGS
  4. Next-level tick bite avoidance tips

Presenters:

Sharon Forsyth, Executive Director, Alpha-gal Alliance; Candice Matthis, Co-founder, Alpha-gal Foundation; Debbie Nichols, Co-founder, Alpha-gal Foundation

AGRISAFE WEBINAR SLIDES

Download PDF of the Agrisafe webinar slides

Resources

Support group

Farmers and Ranchers with Alpha-gal Syndrome

A support group for farmers and ranchers with alpha-gal syndrome.

AGS Patient factsheet

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Click image to enlarge

Download Patient Factsheet PDF

Avoiding tick bites

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Click image to enlarge

Download Avoiding Tick Bites PDF

References

1. Lang M, Corriger J, Haumonte Q, et al. Allergie à α-galactose : un vêlage à fleur de peau. Rev Fr Allergol (2009). 2018;58(3):253. 

2. Nuñez-Orjales R, Martin-Lazaro J, Lopez-Freire S, Galan-Nieto A, Lombardero-Vega M, Carballada-Gonzalez F. Bovine Amniotic Fluid: A New and Occupational Source of Galactose-α-1,3-Galactose. J Investig Allergol Clin Immunol. 2017;27(5):313-314. 

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